Purification Manager, Head
Job Locations US-MD-Silver Spring
# of Openings : 1
Type : Regular Full-Time
CAMRIS International is an medical research and development firm that realizes innovative solutions to health and development challenges through high-quality, cost-effective program and research management services. We combine our proven systems with today’s most effective, evidence-based best practices to improve the lives of people around the world. Our core practice areas include HIV/AIDS, microbiology and infectious disease research, vaccine research, development and production, global health security, biodefense, and clinical research.
CAMRIS is seeking a Purification Manager who will lead the Purification Section at a Bioproduction Facility in Silver Spring, MD. S/he will perform duties associated with the downstream processing and purification of cells and cell products for use in human vaccines and biological products.
*This is a forecasted position and it is contingent upon contract award.
As a Section manager, directs the planning and scheduling of purification of desired products.
Make recommendations for purification of desired products based on research data received from research personnel. If necessary, will advise on further research to be conducted by appropriate personnel and/or work with the personnel to perfect purification processes.
Responsible for perfecting purification procedures that will result in optimal recoveries. Starting materials will be concentrated suspensions of bacteria, yeast, mammalian cells, or insect cells.
Depending on the desired product, will harvest cells intact, or when desired, process cells through various stages of downstream processing using appropriate equipment to accomplish this.
Write Standard Operating Procedures, Batch Production Records, and any other documents that are required to maintain documentation and compliance with current Good Manufacturing Procedures.
MS degree in Biochemistry or the Life Sciences with at least 10 years’ experience in scaled purification.
Must have recent certification of training in GMP regulations.
Professional knowledge of the principles and practices applicable to purification and downstream processing of materials for vaccines destined for clinical testing.
Knowledge of operation of centrifuges (large and small-scale), ultrafiltration, and cell disruption equipment.
Knowledge of column chromatography and other purification methodologies.
Knowledge of facility support equipment such as water for injection, RODI water, and Hepa filtration HVAC systems.
Familiarity with related fields such as general microbiology, physical chemistry, and biochemistry.
Extensive knowledge of Good Manufacturing Practices as applied to biological products.
All proposed personnel to perform services contractor must verify employment eligibility (E-Verify) and obtain a favorable National Agency Check (NACI).